What Our Cell Biologists Can Do
InfinixBio’s diverse team of scientists has expertise working with early-stage therapeutics and diagnostics, human diseases, stem cells, developmental biology and molecular biology.
Our scientific insights let us solve tough problems in cell biology including:
Mammalian Cell Culture/Engineering
- Stable cell line development
- Primary cell culture
- Expression systems
- CRISPR gene editing, knockouts and knock-in
- RNA therapeutics
- Cell signaling and reporter systems
- Complex cell function activation
Cell Function Analysis
- Cytokine expression and receptor activation
- Single Cell analysis by confocal or fluorescence microscopy
- Cell viability assays
- Cytotoxicity studies
- FACS and ELISpot assays
- FISH technology
- Custom tissue staining
- Evaluation/monitor cancer immunotherapy
- Personalized medicine support
We’ll assemble a team of scientists to advance your biotechnology.
Some of the areas we’ve proven our ability to accelerate development include:
To develop a biosensor, we took a T cell and engineered the T cell receptor to create a universal detector. This technology was used to make a reporter system to detect and quantify important targets.
In support of a clinical trial, we analyzed patient cell production of key cytokines. We also established cell proliferation assays and FACS analysis of cell surface markers to demonstrate effective tumor cell killing by the novel therapeutic.
Our understanding of companion diagnostics can aid in selecting which patients are best suited for Phase III trials.
Using activated immune cells, we measured the ability of these cells to make key cell signaling molecules. These results advanced the project to its next stage.
Using cells from the immune system we demonstrated proliferation and differentiation of activated cytotoxic T cells. This enables the analysis of killing patient-specific tumor cells.
Clinical trial support
Success in assisting our clients through the clinical trial phases is our top priority. In addition to GLP compliance, we provide the deep scientific understanding that can help you develop a companion diagnostic for your trial and support your application to the FDA.